It’s the end of an era.

TMZ reports that Angelina Jolie has filed for divorce after 12 years together and two years of marriage.

The gossip site reports that the Mr. and Mrs. Smith co-stars’ rift began over a conflict involving their children.

Jolie cited irreconcilable differences in documents filed Monday.

The 41-year-old actress is asking for physical custody of their six kids.

Jolie is reportedly not asking for spousal support.

However, Jolie reportedly does not want Pitt to have any physical custody of his kids, only legal custody. TMZ reports a source said Jolie “was extremely upset with his methods” of parenting.

Meanwhile, Jolie’s dad, actor Jon Voight, told INSIDE EDITION he thinks it took something big for his daughter to make this move.

“It’s very sad,” the Midnight Cowboy star said Tuesday. “Something very serious must have happened for Angie to make a decision like this.”

The 77-year-old said he learned the news not from Angelina, with whom his relationship has been strained at times over the years, but from his son.

“I am concerned for Angie and the children and hopefully I will be seeing them very soon,” he said.

For INSIDE EDITION’s full report, tune in on Tuesday, September 20 at 6:30pm